Basic Information
VIS ID
TVIS44013805
Fusion event
HTLV-1-LOC102723576 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q23
Reference genome
GRCh37/hg19
Start
100303553/99382396 (Hg38)
End
100303553/99382396 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC102723576
Nearest miRNA
hsa-mir-12113/Upstream/384936; hsa-mir-1243/Downstream/1858399;
Nearest TSS
ENST00000502981/Upstream/29369; ENST00000503257/Downstream/33478;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/293418, chr4-CpG: 40/Downstream/181174
Nearby gene
ADH1C(-29351) ;
Upstream sequence
ACCAGGGTAAATCAGGTAGCTTAGTAGAATGTTGAATCATGAAAGAAGTAACAACAAATTGCATGCACTTCACAATTTTTTCTCATACCCTTCTTTACTG
Downstream sequence
GGACTAACACTTGGGAAGGAACCTTAATCTTAGTGCTAAAGCAACAGCTTAGGTTTTAGTATTTCTCTTGCTGGAGAACTCTACTGTTGAAGGAGATAAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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