Basic Information
VIS ID
TVIS44013829
Fusion event
HTLV-1-LOC107986953 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
83592184/82679949 (Hg38)
End
83592184/82679949 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107986953
Nearest miRNA
hsa-mir-12123/Upstream/2438476; hsa-mir-10400/Downstream/8525536;
Nearest TSS
ENST00000518652/Upstream/2796; ENST00000524359/Downstream/232155;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/837708, chr8-CpG: 49/Downstream/1504575
Nearby gene
LINC01419(No orient, 723809)
Upstream sequence
TACACATTTACCTTGATTAACTCTCGAACATGGTATAAATATCAGCATACACATTCCTTCCACAAGGAATTCTCTACTCCTCAAAGATGGGATAGATACT
Downstream sequence
CTCCTCGTATTTCAATttttctgtgtccccactagatattacttccctaacaaaagagattatgtgatttttgaatgctgcattcccagaaattttgaac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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