Basic Information
VIS ID
TVIS44013840
Fusion event
HTLV-1-chrY integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrY
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
13436462/11280786 (Hg38)
End
13436462/11280786 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3690-2/Upstream/6674558; hsa-mir-12120/Downstream/2198391;
Nearest TSS
ENST00000430575/Upstream/1369988; ENST00000417071/Downstream/1381548;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/65744, chrY-CpG: 92/Downstream/26129
Upstream sequence
GGGTAGAAGGGAATTATGTCTAGTGACATAGATTTGCTATGCTTATCTGACGAAAAATCTCCCTCATGATTTTCAAATCAGATGCATAACTGCATTTAAT
Downstream sequence
GAGTGTCACGAATCATTAATATCAGTCTCTGAAAACAGGATCATTAAAAATGATTAAGATTTTCAACAACAAAGATTTTATCTAAATATTAAGGAAATTA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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