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VISDB
Viral Integration Site DataBase
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TVIS44013878
Basic Information
VIS ID
TVIS44013878
Fusion event
HTLV-1-DBNDD2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
44038757/45410117 (Hg38)
End
44038757/45410117 (Hg38)
Orient
-
Location type
Exonic
Target gene
DBNDD2
miRNAs that regulate target gene
hsa-let-7b-5p
;
hsa-mir-7847-3p
;
hsa-mir-6880-5p
;
hsa-mir-6894-5p
;
hsa-mir-7154-3p
;
hsa-mir-765
;
hsa-mir-766-5p
;
hsa-mir-4785
Nearest miRNA
hsa-mir-103a-2/Upstream/1001914; hsa-mir-1-1/Downstream/15393;
Nearest TSS
ENST00000382410/Upstream/1828;
ENST00000639194/Downstream/5950;
Nearest CpG islands
None/Target,
chr20-CpG: 39/Upstream/2803
,
chr20-CpG: 46/Downstream/5895
Upstream sequence
gactcctccACCAACCTGCATAGCCCAAATCCAAGTGATGATGGAGCAGATACGCCCTTGGCACAGTCGGATGAAGAGGAGGAAAGGGGTGATGGAGGGG
Downstream sequence
CAGAGCCTGGAGCCTGCAGCTAGCAGTGGGCCCCTGCCTACAGACTGACCACGCTGGCTATTCTCCACATGAGACCACAGGCCCAGCCAGAGCCTGTCGG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL186
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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