Basic Information
VIS ID
TVIS44013891
Fusion event
HTLV-1-chr15 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q26.2
Reference genome
GRCh37/hg19
Start
96631255/96088026 (Hg38)
End
96631255/96088026 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105369212 ; LOC112268156
Nearest miRNA
hsa-mir-10393/Upstream/3183551; hsa-mir-1302-10/Downstream/245235;
Nearest TSS
ENST00000557528/Upstream/3442; ENST00000560176/Downstream/37982;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/760933, chr15-CpG: 151/Downstream/233626
Nearby gene
NR2F2-AS1(No orient, 39334)
Upstream sequence
TCAACTAGTTTCCTTAGCCTCTGCTGCTTTGTCTTAATAACCATTTATTTCTGTCTGCCTATTACGTTAATACTGAAATCTTGCATTTGTTTCATATTCA
Downstream sequence
CCTTCCCCCTTCTCTAACCTCATTTCTGTTATTAACTACCCATTGTATTATGATATGATTTTTCCAGGAAACTAGACAGTTCTAAATTTGTCCTTTCTCC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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