Basic Information
VIS ID
TVIS44013898
Fusion event
HTLV-1-SUSD4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q41
Reference genome
GRCh37/hg19
Start
223410716/223237374 (Hg38)
End
223410716/223237374 (Hg38)
Orient
+
Location type
Intronic
Target gene
SUSD4
miRNAs that regulate target gene
hsa-mir-218-5p
Nearest miRNA
hsa-mir-101-1/Upstream/3036755; hsa-mir-1182/Downstream/1019666;
Nearest TSS
ENST00000473358/Upstream/6627; ENST00000366875/Downstream/55195;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/94027, chr1-CpG: 183/Downstream/126126
Upstream sequence
gatgatcatgtcccctgtgaaaaagatagttttatttctttctttccaatctatatatcttttatttccttttcttgccttattgcattaactagaactt
Downstream sequence
ccagtatgatgctgaaacggagtgatgagaaagaacatccttgccttgtccctgatcttacgggaaaacttctagtttctcttcattaagcgtgatgtta
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate