Basic Information
VIS ID
TVIS44013913
Fusion event
HTLV-1-LOC105370802 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
46029231/45737033 (Hg38)
End
46029231/45737033 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105370802
Nearest miRNA
hsa-mir-10393/Upstream/303904; hsa-mir-11181/Downstream/3432037;
Nearest TSS
ENST00000557528/Upstream/31838; ENST00000559148/Downstream/956255;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/31827, chr15-CpG: 96/Downstream/1447139
Nearby gene
SQOR(+45739) ;
Upstream sequence
AAATAACCTGCTTAAGATCTTGAAGTAATGAGTGTTTTTAGCTCCCCTTTCTCCTGGCAGAGGTTGTCCCTTAAAGACAGGGATATTAAaggttcataat
Downstream sequence
ctcttattctaaaagttggggcaggtaggtttcagaattccaaagcatttgaattttggaaatgtaacatatatgtttccatgcagtagagcttagggaa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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