VISDB Viral Integration Site DataBase

VIS ID

TVIS44013914

Fusion event

HTLV-1-NFAT5 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr16

Cytoband

q22.1

Reference genome

Start

End

69663295/69629392 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-31-5p ; hsa-mir-24-3p ; hsa-mir-335-5p ; hsa-mir-21-5p ; hsa-mir-877-5p ; hsa-mir-652-3p ; hsa-mir-17-5p ; hsa-mir-211-5p ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-4690-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-103a-2-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-519a-3p ; hsa-mir-580-5p ; hsa-mir-651-3p ; hsa-mir-889-3p ; hsa-mir-1252-5p ; hsa-mir-4476 ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-6815-3p ; hsa-mir-6826-5p ; hsa-mir-6876-5p ; hsa-mir-3910 ; hsa-mir-548an ; hsa-mir-1468-3p ; hsa-mir-548p ; hsa-mir-921 ; hsa-mir-3174 ; hsa-mir-3609 ; hsa-mir-548ah-5p ; hsa-mir-6507-3p ; hsa-mir-4796-3p ; hsa-mir-374a-5p ; hsa-mir-155-5p ; hsa-mir-7111-5p ; hsa-mir-6883-5p ; hsa-mir-6825-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-766-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-1827 ; hsa-mir-4419a ; hsa-mir-5681a ; hsa-mir-205-5p ; hsa-mir-4536-5p ; hsa-mir-6770-5p ; hsa-mir-6073 ; hsa-mir-1253 ; hsa-mir-552-3p ; hsa-mir-6768-5p ; hsa-mir-6505-5p ; hsa-mir-6844 ; hsa-mir-9-5p ; hsa-mir-1-3p ; hsa-mir-206 ; hsa-mir-613 ; hsa-mir-6124 ; hsa-mir-3175 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6878-5p ; hsa-mir-3202 ; hsa-mir-4756-5p ; hsa-mir-3179 ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-6760-5p ; hsa-mir-6873-5p ; hsa-mir-4797-3p ; hsa-mir-6512-5p ; hsa-mir-3941 ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-4261 ; hsa-mir-4496 ; hsa-mir-146a-5p ; hsa-mir-3180-5p ; hsa-mir-345-5p ; hsa-mir-4256 ; hsa-mir-4706 ; hsa-mir-4749-5p ; hsa-mir-4762-3p ; hsa-mir-520a-5p ; hsa-mir-525-5p ; hsa-mir-6731-3p ; hsa-mir-744-5p ; hsa-mir-1273h-5p ; hsa-mir-17-3p ; hsa-mir-30b-3p ; hsa-mir-3160-3p ; hsa-mir-3192-5p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-3689d ; hsa-mir-4311 ; hsa-mir-4443 ; hsa-mir-4487 ; hsa-mir-485-5p ; hsa-mir-490-3p ; hsa-mir-558 ; hsa-mir-6134 ; hsa-mir-6499-3p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6799-5p ; hsa-mir-6851-5p ; hsa-mir-6880-5p ; hsa-mir-6884-5p ; hsa-mir-7106-5p ; hsa-mir-7847-3p ; hsa-mir-7851-3p

Nearest miRNA

hsa-mir-1225/Upstream/63524; hsa-mir-11401/Downstream/303689;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/62559, chr16-CpG: 19/Downstream/96998

Upstream sequence

TTTTTGTTGTTTAATTTTTTAAAATGTGTTTCTCAGATTCACCAATTTAGATTTTTTTCCTCTTCCTGTTACTAAGGGAATAAGTAAATATGATGCTGCT

Downstream sequence

AATCCACAATCCAGAATATTGGGTAAAAGAGCGTCTATCAAGCCTTTATCTGCTTCTACACAATTCATACTTTTATGCACTCCCATCAATAATATATTTT