Basic Information
VIS ID
TVIS44013925
Fusion event
HTLV-1-chrX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
49888418/50123763 (Hg38)
End
49888418/50123763 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1587/Upstream/109080; hsa-let-7f-2/Downstream/2212794;
Nearest TSS
ENST00000429181/Upstream/42098; ENST00000493507/Downstream/76595;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/200379, chrX-CpG: 16/Downstream/157573
Nearby gene
CLCN5(+24526) ;
Upstream sequence
ccagaaggatgtggcgcgaaacttttcaagtgctgtaagcaaagaactgtcaacccagaattctttttttaaaaaaatttcaacttttattttaggttca
Downstream sequence
gggggtaaaacgtgcaggtttgtaacaagggtatattgcatgatgctgaggtttggggtatgaatgatcctgtcacccaggtagtgagcacagtactcaa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate