VISDB Viral Integration Site DataBase

VIS ID

TVIS44013942

Fusion event

HTLV-1-GTDC1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

q22.3

Reference genome

Start

End

144855281/144097714 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-155-3p ; hsa-mir-8064 ; hsa-mir-483-3p ; hsa-mir-5580-3p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-642a-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-4469 ; hsa-mir-6832-3p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-204-5p ; hsa-mir-211-5p ; hsa-mir-3691-3p ; hsa-mir-3163 ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-4282 ; hsa-mir-4778-5p ; hsa-mir-4279 ; hsa-mir-2355-5p ; hsa-mir-6778-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-122-3p ; hsa-mir-6793-3p ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-6747-3p ; hsa-mir-660-3p ; hsa-mir-939-3p ; hsa-mir-210-3p ; hsa-mir-1257 ; hsa-mir-6716-5p ; hsa-mir-15b-3p ; hsa-mir-2681-3p ; hsa-mir-7856-5p ; hsa-mir-3667-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-101-5p ; hsa-mir-125b-2-3p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-29c-3p ; hsa-mir-6795-3p ; hsa-mir-6826-3p ; hsa-mir-6887-3p

Nearest miRNA

hsa-mir-128-1/Upstream/3511029; hsa-mir-10b/Downstream/5232564;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/160101, chr2-CpG: 127/Downstream/234172

Upstream sequence

CCACTGCAATAATATAGGTGCTGAATACTCTCAATAGGGTGATGAGTGCAACTTCCTTCTGGTTTTAAAAATACTCTCCCCACTGCCCCCAGCTTTAAGT

Downstream sequence

CCTCTGTCAAGAAACTCTGATTTTGACATATCTGGCTTCCTCAGCAATGCTTTTAAACCACTTTATGCTTGCTCCTCCAGTCACAGAAACACTTGTTTCA