Basic Information
VIS ID
TVIS44013957
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p32.1
Reference genome
GRCh37/hg19
Start
59028732/58563060 (Hg38)
End
59028732/58563060 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1B
Nearest miRNA
hsa-mir-12136/Upstream/3337337; hsa-mir-101-1/Downstream/1170167;
Nearest TSS
ENST00000473358/Upstream/16258; ENST00000637377/Downstream/14713;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/16155, chr1-CpG: 168/Downstream/13025
Nearby gene
TACSTD2(-12363) ;
Nearest cancer related gene
TACSTD2(OG, -12363) ;
Upstream sequence
ctttgacaaacctgacaaaaacaagcaatggggaaaggattccctatttaataaatggtgttgggaaaactggctagccatatgtggaaaactgaaacta
Downstream sequence
gacccctttcttacaccttatacaaaaattaactcaagatggattaaagacttaaatgtaagacctaaaaccataaaaaccctagaagaaaacctatgca
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate