VISDB Viral Integration Site DataBase

VIS ID

TVIS44013974

Fusion event

HTLV-1-CDK6 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr7

Cytoband

q21.2

Reference genome

Start

End

92275477/92646163 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-195-5p ; hsa-let-7a-5p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-34b-5p ; hsa-mir-424-5p ; hsa-mir-16-5p ; hsa-mir-34a-5p ; hsa-mir-107 ; hsa-mir-30a-3p ; hsa-let-7b-5p ; hsa-mir-21-5p ; hsa-mir-137 ; hsa-mir-124-3p ; hsa-mir-449a ; hsa-mir-29c-3p ; hsa-mir-34b-3p ; hsa-mir-34c-5p ; hsa-mir-185-5p ; hsa-mir-203a-3p ; hsa-mir-494-3p ; hsa-mir-26a-5p ; hsa-mir-26b-5p ; hsa-mir-191-5p ; hsa-mir-218-5p ; hsa-mir-449b-5p ; hsa-mir-193b-3p ; hsa-mir-103a-3p ; hsa-mir-22-3p ; hsa-mir-1303 ; hsa-mir-615-3p ; hsa-mir-512-5p ; hsa-mir-452-5p ; hsa-mir-378a-3p ; hsa-mir-129-5p ; hsa-mir-129-2-3p ; hsa-mir-145-5p ; hsa-mir-506-3p ; hsa-mir-513a-3p ; hsa-mir-670-3p ; hsa-mir-513c-3p ; hsa-mir-3606-3p ; hsa-mir-6757-3p ; hsa-mir-561-5p ; hsa-mir-4761-5p ; hsa-mir-6801-5p ; hsa-mir-3941 ; hsa-mir-8485 ; hsa-mir-147a ; hsa-mir-1298-5p ; hsa-mir-551b-5p ; hsa-mir-140-3p ; hsa-mir-384 ; hsa-mir-5682 ; hsa-mir-216b-5p ; hsa-mir-548v ; hsa-mir-1179 ; hsa-mir-4310 ; hsa-mir-4291 ; hsa-mir-7157-5p ; hsa-mir-1236-3p ; hsa-mir-214-3p ; hsa-mir-761 ; hsa-mir-922 ; hsa-mir-3619-5p ; hsa-mir-6809-3p ; hsa-mir-373-5p ; hsa-mir-616-5p ; hsa-mir-371b-5p ; hsa-mir-371a-5p ; hsa-mir-372-5p ; hsa-mir-3671 ; hsa-mir-504-5p ; hsa-mir-200a-3p ; hsa-mir-105-5p ; hsa-mir-205-5p ; hsa-mir-4256 ; hsa-mir-6836-5p ; hsa-mir-6821-3p ; hsa-mir-6132 ; hsa-mir-6790-3p ; hsa-mir-4750-3p ; hsa-mir-301b-5p ; hsa-mir-301a-5p ; hsa-mir-4714-5p ; hsa-mir-15b-5p ; hsa-mir-497-5p ; hsa-mir-6838-5p ; hsa-mir-15a-5p ; hsa-mir-498 ; hsa-mir-2054 ; hsa-mir-3915 ; hsa-mir-644a ; hsa-mir-3911 ; hsa-mir-891a-3p ; hsa-mir-3688-5p ; hsa-mir-3928-3p ; hsa-mir-3922-5p ; hsa-mir-4717-5p ; hsa-mir-449c-5p ; hsa-mir-2682-5p ; hsa-mir-4753-5p ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-5587-5p ; hsa-mir-7853-5p ; hsa-mir-7849-3p ; hsa-mir-5197-5p ; hsa-mir-302c-5p ; hsa-mir-302d-5p ; hsa-mir-302b-5p ; hsa-mir-7152-5p ; hsa-mir-183-3p ; hsa-mir-4326 ; hsa-mir-4680-3p ; hsa-mir-1266-3p ; hsa-mir-4724-5p ; hsa-mir-548c-3p ; hsa-mir-4753-3p ; hsa-mir-885-3p ; hsa-mir-942-5p ; hsa-mir-6868-5p ; hsa-mir-6515-3p ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-187-5p ; hsa-mir-6782-3p ; hsa-mir-491-3p ; hsa-mir-3613-5p ; hsa-mir-219a-2-3p ; hsa-mir-5739 ; hsa-mir-5091 ; hsa-mir-6716-3p ; hsa-mir-502-3p ; hsa-mir-501-3p ; hsa-mir-646 ; hsa-mir-8064 ; hsa-mir-4643 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-888-5p ; hsa-mir-302f ; hsa-mir-342-3p ; hsa-mir-3685 ; hsa-mir-607 ; hsa-mir-155-3p ; hsa-mir-548n ; hsa-mir-1972 ; hsa-mir-624-5p ; hsa-mir-500b-3p ; hsa-mir-3159 ; hsa-mir-6871-3p ; hsa-mir-4482-5p ; hsa-mir-3130-5p ; hsa-mir-541-5p ; hsa-mir-5195-3p ; hsa-mir-340-5p ; hsa-mir-491-5p ; hsa-mir-20b-5p ; hsa-mir-34a-3p ; hsa-mir-195-3p ; hsa-mir-214-5p ; hsa-mir-1-5p ; hsa-mir-203a-5p ; hsa-mir-211-5p ; hsa-mir-320a ; hsa-mir-892b ; hsa-mir-3138 ; hsa-mir-3663-3p ; hsa-mir-4426 ; hsa-mir-4491 ; hsa-mir-4534 ; hsa-mir-4647 ; hsa-mir-4657 ; hsa-mir-4662b ; hsa-mir-6894-5p ; hsa-mir-7154-3p ; hsa-mir-765 ; hsa-mir-766-5p ; hsa-mir-767-5p ; hsa-mir-7847-3p ; hsa-mir-8082 ; hsa-mir-4693-3p ; hsa-mir-621 ; hsa-mir-6761-5p ; hsa-mir-7855-5p

Nearest miRNA

hsa-mir-10525/Upstream/442065; hsa-mir-10399/Downstream/836597;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/55604, chr7-CpG: 316/Downstream/186724

Nearest cancer related gene

CDK6(OG, No orient, 0)

Upstream sequence

GCTTGCCTAATGAAGTTCTTGTTAAATATCCAATCAAACATCTTCAAAATCCAGCTCAGGACTAACTTCAGGAAGCCCCTATTATTCTAGTTCAGGGTAA

Downstream sequence

TATCTGACTTTTCTAAGCTCTTAACAGTTTTAAAAATCTGTACCATGTGGCTCAGCACTTACATATGCCTGGTCTGATACTGTTTGCTAATTATTACATG