Basic Information
VIS ID
TVIS44013981
Fusion event
HTLV-1-chr17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p12
Reference genome
GRCh37/hg19
Start
12387754/12484437 (Hg38)
End
12387754/12484437 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA17A
Nearest miRNA
hsa-mir-1253/Upstream/402441; hsa-mir-10226/Downstream/432831;
Nearest TSS
ENST00000595228/Upstream/282837; ENST00000577679/Downstream/65345;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/462883, chr17-CpG: 70/Downstream/180913
Nearby gene
LINC00670(No orient, 65531)
Upstream sequence
GAGTCACACATTTATCCAGCTTTATAGTCTCCTTTCAGGTTGAGCCGTGGTCCCTGAAGTCCTCAAAGATATTTAACACTCCCTTTTTTTGAGGGTGAAG
Downstream sequence
TAAATAACTGGCAAAATAATGTTGCCATAGATCTTCTCTGAGGAAATTGCAGCAcagatggagtatccttaatttggaaatccaaaatgcaaaacttttt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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