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TVIS44014008
Basic Information
VIS ID
TVIS44014008
Fusion event
HTLV-1-CHAC1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q15.1
Reference genome
GRCh37/hg19
Start
41240553/40948355 (Hg38)
End
41240553/40948355 (Hg38)
Orient
-
Location type
Intronic
Target gene
CHAC1
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-26a-5p
;
hsa-mir-26b-5p
;
hsa-mir-95-5p
;
hsa-mir-142-5p
;
hsa-mir-498
;
hsa-mir-561-3p
;
hsa-mir-1297
;
hsa-mir-4465
;
hsa-mir-4697-3p
;
hsa-mir-548at-5p
;
hsa-mir-5590-3p
;
hsa-mir-5697
;
hsa-mir-15a-5p
;
hsa-mir-16-5p
;
hsa-mir-15b-5p
;
hsa-mir-195-5p
;
hsa-mir-363-5p
;
hsa-mir-424-5p
;
hsa-mir-491-5p
;
hsa-mir-497-5p
;
hsa-mir-661
;
hsa-mir-374b-3p
;
hsa-mir-1293
;
hsa-mir-3151-5p
;
hsa-mir-3170
;
hsa-mir-4447
;
hsa-mir-4472
;
hsa-mir-4483
;
hsa-mir-4524a-5p
;
hsa-mir-4524b-5p
;
hsa-mir-6742-5p
;
hsa-mir-6742-3p
;
hsa-mir-6745
;
hsa-mir-6756-5p
;
hsa-mir-6766-5p
;
hsa-mir-6776-5p
;
hsa-mir-6796-5p
;
hsa-mir-6838-5p
;
hsa-mir-6855-5p
;
hsa-mir-7847-3p
;
hsa-mir-211-3p
;
hsa-mir-940
;
hsa-mir-1207-5p
;
hsa-mir-1324
;
hsa-mir-3166
;
hsa-mir-3199
;
hsa-mir-4251
;
hsa-mir-4514
;
hsa-mir-4692
;
hsa-mir-4722-5p
;
hsa-mir-4740-5p
;
hsa-mir-4763-3p
;
hsa-mir-4524b-3p
;
hsa-mir-6165
;
hsa-mir-6733-3p
;
hsa-mir-6808-5p
;
hsa-mir-6857-3p
;
hsa-mir-6868-5p
;
hsa-mir-6893-5p
;
hsa-mir-8052
;
hsa-mir-383-3p
;
hsa-mir-503-5p
;
hsa-mir-646
;
hsa-mir-4755-3p
;
hsa-mir-4311
;
hsa-mir-656-5p
;
hsa-mir-5006-5p
;
hsa-mir-6501-5p
;
hsa-mir-144-3p
;
hsa-mir-194-5p
;
hsa-mir-4298
;
hsa-mir-1302
;
hsa-mir-3972
;
hsa-mir-1202
;
hsa-mir-5196-5p
;
hsa-mir-4747-5p
;
hsa-mir-4646-5p
;
hsa-mir-204-3p
;
hsa-mir-6871-5p
;
hsa-mir-4494
;
hsa-mir-4463
;
hsa-mir-212-3p
;
hsa-mir-132-3p
;
hsa-mir-539-5p
;
hsa-mir-7109-3p
;
hsa-mir-5001-5p
;
hsa-mir-762
;
hsa-mir-4498
;
hsa-mir-4492
;
hsa-mir-4743-5p
;
hsa-mir-6894-5p
;
hsa-mir-765
;
hsa-mir-7154-3p
;
hsa-mir-766-5p
;
hsa-mir-5703
;
hsa-mir-4516
;
hsa-mir-4434
;
hsa-mir-4784
;
hsa-mir-3150b-3p
;
hsa-mir-6770-5p
;
hsa-mir-6784-5p
;
hsa-mir-4446-3p
;
hsa-mir-3154
;
hsa-mir-3650
;
hsa-mir-193b-5p
;
hsa-mir-4302
;
hsa-mir-224-5p
;
hsa-mir-5692a
;
hsa-mir-328-5p
;
hsa-mir-3663-5p
;
hsa-mir-625-5p
;
hsa-mir-637
;
hsa-mir-6795-5p
;
hsa-mir-6885-5p
;
hsa-mir-6887-5p
;
hsa-mir-7109-5p
;
hsa-mir-7152-3p
Nearest miRNA
hsa-mir-1233-1/Upstream/3975454; hsa-mir-10393/Downstream/743230;
Nearest TSS
ENST00000557528/Upstream/17475;
ENST00000444189/Downstream/4607;
Nearest CpG islands
None/Target,
chr15-CpG: 55/Upstream/6162
,
chr15-CpG: 96/Downstream/4332
Nearby gene
CHAC1
(+5083) ;
Upstream sequence
TGCAAGAGAGTTAAATGGTCCAAAGAGAGTGATGGCTTCTCATTTTCTGTCCCTTACAGAGACTACAAATATCATTTCTTCTGGAATCTAGCACATTTCC
Downstream sequence
AAAATGCATCACTTATATTTTCCTCACAAGGCAGGCACACATTAAGCACGTGACAATCATATGATTTATTTGTGAGCCCCAGGGCTTCCAGGAGCTTTCC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL202
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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