Basic Information
VIS ID
TVIS44014010
Fusion event
HTLV-1-GRIK1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
31093343/29721024 (Hg38)
End
31093343/29721024 (Hg38)
Orient
-
Location type
Intronic
Target gene
GRIK1
Nearest miRNA
hsa-let-7c/Upstream/2766981; hsa-mir-3197/Downstream/654270;
Nearest TSS
ENST00000624081/Upstream/63618; ENST00000455392/Downstream/27151;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/421559, chr21-CpG: 61/Downstream/218044
Upstream sequence
tgagaatctcattaaccaggtaagattaaactcctatcaccggagaggagactggaagttgaccccactcccagacagactttgtctcaggctatcacct
Downstream sequence
attcttccgagggctcattcctctttccccaaaatcatttactctccccctaagttgcttacatccccctcccctctcccctatgaagaaggtgtataag
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate