Basic Information
VIS ID
TVIS44014022
Fusion event
HTLV-1-LOC107984625 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
60081246/59507112 (Hg38)
End
60081246/59507112 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA13B ; FRA13C
Target gene
LOC107984625
Nearest miRNA
hsa-mir-1297/Upstream/4332564; hsa-mir-1267/Downstream/1692686;
Nearest TSS
ENST00000623511/Upstream/1273995; ENST00000435636/Downstream/189081;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1872316, chr13-CpG: 52/Downstream/656414
Nearby gene
DIAPH3(-158475) ;
Upstream sequence
ccttcacacacagttgttcaccaaatactattgatttttcctcttaaatacgtcttaacagctctactcaagtctatcttcactttcattgctacagtta
Downstream sequence
gggcgctcatcattactttcctgaattgtagtaagggattccactcctaatttacctcatcacctctgctatactcttgtcTTAAATTTGTCCTCCAGAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate