Basic Information
VIS ID
TVIS44014067
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
101913390/100901162 (Hg38)
End
101913390/100901162 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12123/Upstream/198138; hsa-mir-10400/Downstream/1224270;
Nearest TSS
ENST00000518652/Upstream/178353; ENST00000514926/Downstream/23826;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/178168, chr8-CpG: 249/Downstream/49254
Nearby gene
YWHAZ(-17414) ;
Nearest cancer related gene
YWHAZ(OG, -17414) ;
Upstream sequence
gatctacactgggtttcaaagacttagtatgacaaaaattataatgtaccttattaacatttttaatgttgagttcatgttgaaatagtatttttgatat
Downstream sequence
attgggttaaagaaaacatcatttaaattaatttcaggttaggtgaggtggctcatgcctgtaatcctagcactttgggaggccaaggcaggaggattgc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate