Basic Information
VIS ID
TVIS44014089
Fusion event
HTLV-1-DLGAP2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p23.3
Reference genome
GRCh37/hg19
Start
1084374/1134374 (Hg38)
End
1084374/1134374 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
DLGAP2
miRNAs that regulate target gene
hsa-mir-6738-3p ; hsa-mir-544a ; hsa-mir-20a-3p ; hsa-mir-578 ; hsa-mir-526b-5p ; hsa-mir-4764-5p ; hsa-mir-627-3p ; hsa-mir-4635
Nearest miRNA
hsa-mir-10400/Downstream/666751;
Nearest TSS
ENST00000518652/Upstream/29492; ENST00000522989/Downstream/114386;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/30570, chr8-CpG: 15/Downstream/10376
Upstream sequence
ttgtgaatagtgctgcaatgaacgtgcatgtgtcttagtggtagaacgatgtatattcctttgggtttatacccagtcatgggattgcttggtgcaatgg
Downstream sequence
tagttctgtttttaggtctttgaggcatcaccactctgtcttccacaatggttgagtaatttacactcccaccaacagtgtataagcaattccttttttt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate