Basic Information
VIS ID
TVIS44014108
Fusion event
HTLV-1-NOD1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
30488874/30449258 (Hg38)
End
30488874/30449258 (Hg38)
Orient
-
Location type
Intronic
Target gene
NOD1
miRNAs that regulate target gene
hsa-mir-1250-3p ; hsa-mir-34a-5p
Nearest miRNA
hsa-mir-1183/Upstream/159368; hsa-mir-10399/Downstream/2283723;
Nearest TSS
ENST00000635602/Upstream/1281; ENST00000583191/Downstream/29378;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/163233, chr7-CpG: 68/Downstream/29113
Upstream sequence
GATAACAAGTAAAAGGCTGAACAATTAAAAGCTTGATTTTTAGGCCACATCAAAATGATCAAGTCAGACACTCTGGACCCTTTCCCTCAGAGTCCCCAGC
Downstream sequence
TTGGTGCTGGGAAATAGTGTGTATGTACATGGCATGGCCAGCCCAAGACAgcacaggctgctagacattcccaatatctatactttcttagcaatagatt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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