Basic Information
VIS ID
TVIS44014129
Fusion event
HTLV-1-PARVB integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.31
Reference genome
End
44489170/44093290 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1281/Upstream/2169993; hsa-let-7a-3/Downstream/1107664;
Upstream sequence
ATTCCTCCCTGGTGGATGTGGCTGAAAGGCCTGCAGGGTCTCACTGGTGCAGGGAGATGAGGGGTCATTTCTGGTTCTGGGATTGTCCCTAATCACTGGG
Downstream sequence
CGTTCCAGATCCTGTAACTGTTCAGCACTCCCTTGAGACAGGAGGTCATGGTGTTTCTGACTTGGAGCCTCTGGCTCTCTTTATTAGATTCTGTTGCATG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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