Basic Information
VIS ID
TVIS44014146
Fusion event
HTLV-1-CHRM3-AS2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q43
Reference genome
GRCh37/hg19
Start
239873205/239709905 (Hg38)
End
239873205/239709905 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
CHRM3-AS2
Nearest miRNA
hsa-mir-101-1/Upstream/2238714; hsa-mir-3123/Downstream/1422367;
Nearest TSS
ENST00000473358/Upstream/2383; ENST00000448020/Downstream/9161;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/321866, chr1-CpG: 105/Downstream/287632
Upstream sequence
TAAATTCTCATTCTTGACAAAGCTACCTTGTTTTATCTTTTCTTTAAACCTCAAGTGttttaaaaaaattaatatcaaaatgtaaaataatatCCACATT
Downstream sequence
ATTTAAGTTAAAATGATATTAATTGCTATTTGACATGAAGCATCATTGTATCATGAGATATTACTAAAGGTAACTCTGCAGTCCTCCTCCACCTATGCCA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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