Basic Information
VIS ID
TVIS44014148
Fusion event
HTLV-1-LOC105378314 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
59527999/57768239 (Hg38)
End
59527999/57768239 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10C
Target gene
LOC105378314
Nearest miRNA
hsa-mir-1265/Upstream/463680; hsa-mir-107/Downstream/5604718;
Nearest TSS
ENST00000439456/Upstream/1406964; ENST00000489785/Downstream/499695;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/1406725, chr10-CpG: 34/Downstream/338382
Nearby gene
IPMK(-423279) ;
Upstream sequence
caatatctacaaaaaacctacaactaacatcacacctaatggtaagaaatttgaagatttcctacttagatcaagaacaaggcaaggatgtgtcttctta
Downstream sequence
ccttcctttccaatattatactggaagtactagcaaatacaataagacaagaaaaaaataaaaggtatacatactgggaaggaagaaataaaactgtctt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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