VISDB Viral Integration Site DataBase

VIS ID

TVIS44014185

Fusion event

HTLV-1-EXTL3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr8

Cytoband

p21.1

Reference genome

Start

End

28552913/28695396 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-500a-5p ; hsa-mir-125b-5p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-99a-5p ; hsa-mir-4474-3p ; hsa-mir-644a ; hsa-mir-6505-3p ; hsa-mir-617 ; hsa-mir-4673 ; hsa-mir-4302 ; hsa-mir-4645-5p ; hsa-mir-199a-5p ; hsa-mir-199b-5p ; hsa-mir-6828-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-642a-5p ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-6090 ; hsa-mir-6827-5p ; hsa-mir-505-5p ; hsa-mir-6847-3p ; hsa-mir-767-3p ; hsa-mir-6728-3p ; hsa-mir-4469 ; hsa-mir-6870-3p ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-4793-5p ; hsa-mir-5196-3p ; hsa-mir-141-5p ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-566 ; hsa-mir-6789-3p ; hsa-mir-134-3p ; hsa-mir-7114-5p ; hsa-mir-4315 ; hsa-mir-101-3p ; hsa-mir-1276 ; hsa-mir-1323 ; hsa-mir-548o-3p

Nearest miRNA

hsa-mir-124-1/Upstream/190214; hsa-mir-10400/Downstream/1261876;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/72115, chr8-CpG: 145/Downstream/5675

Nearby gene

EXTL3-AS1(No orient, 3007)

Nearest cancer related gene

EXTL3(TSG, No orient, 0)

Upstream sequence

ttttgtatttttagtagagatggggtttcaccatgttggtcaggctggtcttgaactcctgaccttgtgatacacccgcctcggcctcctaaagtgctgg

Downstream sequence

gattaTGAGGATTTTTTAAATAGTAAGGCTACATAAGCAATCACGTGGACACCCAGTGTCACCTGGGACATGTGGGTACCACAGGTCAATGTCAACAGCC