Basic Information
VIS ID
TVIS44014204
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
95022457/94556901 (Hg38)
End
95022457/94556901 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1D
Nearest miRNA
hsa-mir-101-1/Upstream/13122; hsa-mir-11399/Downstream/3488341;
Nearest TSS
ENST00000473358/Upstream/15101; ENST00000422520/Downstream/35396;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/14818, chr1-CpG: 70/Downstream/263145
Nearby gene
F3(-15044) ;
Upstream sequence
GCAATTCTAAATCAGAATAGCATCTAATAGACTGCATATGAAATGTGTTTACTATCTTCAAATATTTTCTGGCCTATTCATTAAGTACTCAAtatttatt
Downstream sequence
tatttatttatttaatttattttttaagacagggtttccctcttgttgcccaggctatagtacaatggtatgatctcagctcactgcaacctctgcctcc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate