Basic Information
VIS ID
TVIS44014229
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
124033888/124163181 (Hg38)
End
124033888/124163181 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7a-2/Upstream/781669; hsa-mir-3167/Downstream/2825277;
Nearest TSS
ENST00000527297/Upstream/45686; ENST00000318666/Downstream/20164;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/421344, chr11-CpG: 44/Downstream/459587
Nearby gene
VWA5A(+16270) ;
Nearest cancer related gene
VWA5A(TSG, +16270) ;
Upstream sequence
aaaattattattttaattaCTGTTTTGCTAATAACCTATAATAATGATACCATCAAAAAGCCATTCTTTATTGTCCTGTTGGATGTCTGtttttaaaaaa
Downstream sequence
tatttttattaaatattaaacatttagaaaataataCTCATGAAAAatatgtaaaatataaggaactgtgatacaatgatacaatgaacacatgcatccc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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