Basic Information
VIS ID
TVIS44014239
Fusion event
HTLV-1-SRP14-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q15.1
Reference genome
GRCh37/hg19
Start
40348161/40055960 (Hg38)
End
40348161/40055960 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
SRP14-AS1
Nearest miRNA
hsa-mir-1233-1/Upstream/3083059; hsa-mir-10393/Downstream/1635625;
Nearest TSS
ENST00000557528/Upstream/16611; ENST00000559012/Downstream/8427;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/16598, chr15-CpG: 44/Downstream/52696
Upstream sequence
AAAGCCCCACTCCCCACTAAGAGACAACTCCCCATACCAGAGCAGGAAGAGAGAGGGCGATTGAGCAAAGGAGGCCTGAGGGGAAACAGAGACACCCATC
Downstream sequence
TACAGGAGCCCCTGAGTCAGGTGTGGGAGGAGGGAGAGGCAGGGCCCAGCAGAAGCCACCGTTTGCGCCACACTCCTCTACCTCAGGCGGAGACCAGCTG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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