VISDB Viral Integration Site DataBase

VIS ID

TVIS44014241

Fusion event

HTLV-1-PYGO1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr15

Cytoband

q21.3

Reference genome

Start

End

55849838/55557640 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-128-3p ; hsa-mir-122-5p ; hsa-mir-6832-5p ; hsa-mir-6124 ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4768-3p ; hsa-mir-500b-3p ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125 ; hsa-mir-7158-3p ; hsa-mir-4539 ; hsa-mir-889-3p ; hsa-mir-4733-5p ; hsa-mir-186-3p ; hsa-mir-4724-5p ; hsa-mir-1278 ; hsa-mir-5583-5p ; hsa-mir-8054 ; hsa-mir-3129-3p ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n ; hsa-mir-574-5p ; hsa-mir-371a-5p ; hsa-mir-6796-5p ; hsa-mir-7109-5p ; hsa-mir-6867-5p ; hsa-mir-6742-5p ; hsa-mir-4447 ; hsa-mir-4472 ; hsa-mir-3151-5p ; hsa-mir-491-5p ; hsa-mir-3650 ; hsa-mir-4455 ; hsa-mir-6747-5p ; hsa-mir-7110-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6885-5p ; hsa-mir-6887-5p ; hsa-mir-328-5p ; hsa-mir-6795-5p ; hsa-mir-134-3p ; hsa-mir-4318 ; hsa-mir-7641 ; hsa-mir-1290 ; hsa-mir-876-5p ; hsa-mir-3167 ; hsa-mir-4695-3p ; hsa-mir-1246 ; hsa-mir-296-3p ; hsa-mir-4694-3p ; hsa-mir-4426 ; hsa-mir-4647 ; hsa-mir-4662b

Nearest miRNA

hsa-mir-10393/Upstream/184606; hsa-mir-11181/Downstream/3613543;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/59084, chr15-CpG: 148/Downstream/29954

Upstream sequence

aaaagagaattttagaccaatctccctgatgaacactgatgcagaaatcctcaataaaatactggcaaaccgaatccagcagcacatcaaaaagcttatc

Downstream sequence

caccatgatcaagtgggcttcatccttgggatgcaaagctggttcaacatatgcaaatcaataaatgtaatccagcatataaacagaaccaaagacaaaa