VISDB Viral Integration Site DataBase

VIS ID

TVIS44014248

Fusion event

HTLV-1-ACACA integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr17

Cytoband

q12

Reference genome

Start

End

35753750/37396796 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-24-3p ; hsa-let-7b-5p ; hsa-mir-193b-3p ; hsa-mir-339-5p ; hsa-mir-324-3p ; hsa-mir-222-3p ; hsa-mir-92a-3p ; hsa-mir-142-3p ; hsa-mir-218-5p ; hsa-mir-4646-3p ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-491-3p ; hsa-mir-4433b-5p ; hsa-mir-1269b ; hsa-mir-1269a ; hsa-mir-580-3p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-4515 ; hsa-mir-1288-3p ; hsa-mir-4740-5p ; hsa-mir-6857-3p ; hsa-mir-219a-2-3p ; hsa-mir-422a ; hsa-mir-378i ; hsa-mir-378h ; hsa-mir-378f ; hsa-mir-378e ; hsa-mir-378d ; hsa-mir-378c ; hsa-mir-378b ; hsa-mir-378a-3p ; hsa-mir-4251 ; hsa-mir-4254 ; hsa-mir-3690 ; hsa-mir-361-3p ; hsa-mir-1250-3p ; hsa-mir-1255b-2-3p ; hsa-mir-1207-5p ; hsa-mir-1282 ; hsa-mir-182-3p ; hsa-mir-211-3p ; hsa-mir-3125 ; hsa-mir-3916 ; hsa-mir-4261 ; hsa-mir-4436b-3p ; hsa-mir-4496 ; hsa-mir-4632-5p ; hsa-mir-4636 ; hsa-mir-4763-3p ; hsa-mir-4777-5p ; hsa-mir-494-3p ; hsa-mir-5002-5p ; hsa-mir-5010-3p ; hsa-mir-5095 ; hsa-mir-518d-5p ; hsa-mir-518e-5p ; hsa-mir-518f-5p ; hsa-mir-519a-5p ; hsa-mir-519b-5p ; hsa-mir-519c-5p ; hsa-mir-520c-5p ; hsa-mir-520g-5p ; hsa-mir-522-5p ; hsa-mir-523-5p ; hsa-mir-526a ; hsa-mir-541-3p ; hsa-mir-5707 ; hsa-mir-592 ; hsa-mir-597-5p ; hsa-mir-654-5p ; hsa-mir-6721-5p ; hsa-mir-6735-5p ; hsa-mir-6758-5p ; hsa-mir-6769a-5p ; hsa-mir-6769b-5p ; hsa-mir-6823-5p ; hsa-mir-6856-5p ; hsa-mir-6859-5p ; hsa-mir-6879-5p ; hsa-mir-7151-3p ; hsa-mir-7843-5p ; hsa-mir-7845-5p ; hsa-mir-92a-2-5p

Nearest miRNA

hsa-mir-1180/Upstream/362983; hsa-mir-10226/Downstream/218135;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/37112, chr17-CpG: 23/Downstream/9928

Upstream sequence

GTACTTATGACTAAAGGCCAGAAGAAATCTTTTTATTTTTTGTTTGCCCTGGACAGGTTGAGAGTCCTATGATCCCTTCCTCCCCATCCCACTGATACTC

Downstream sequence

CACTCCCACTTTCAAAAAGTATTCCATTTTCTGAGTTGACACAATGGCCCTCAGGTTGCCTTGAATTACTTATCTTCCCTATTATTAGTAATAGTAGTAG