Basic Information
VIS ID
TVIS44014260
Fusion event
HTLV-1-chr21 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
27972284/26599965 (Hg38)
End
27972284/26599965 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7c/Upstream/1025921; hsa-mir-3197/Downstream/353996;
Nearest TSS
ENST00000624081/Upstream/26681; ENST00000426771/Downstream/240524;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/26638, chr21-CpG: 147/Downstream/244368
Nearby gene
CYYR1(-26703) ;
Upstream sequence
TTTTTTGACTCATTTTGCATTCGTTTGAGCATTGGGAATATCCCAGTATCATCTTGGGCAGTGGGTGACTTCCATAGTGCCAGACAGCTCTACTGTCTTG
Downstream sequence
GGGAGGTCTTCCGTGACACCTCAGCTCGCTGcagtgaagtgctggctcatgccagctgactgtgtttatctcctcccaactttgcatttgtcaaagagaa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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