Basic Information
VIS ID
TVIS44014286
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q33
Reference genome
GRCh37/hg19
Start
138011718/138326973 (Hg38)
End
138011718/138326973 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10525/Upstream/203152; hsa-mir-10399/Downstream/717127;
Nearest TSS
ENST00000635602/Upstream/163533; ENST00000485318/Downstream/133361;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/324663, chr7-CpG: 146/Downstream/132949
Nearby gene
TRIM24(+133361) ;
Nearest cancer related gene
TRIM24(TSG, +133361) ;
Upstream sequence
agctcatgcaaggtgatacgttatgatagaggtatgatcagagtagtgtgagaaaacagaagaggTTCTATTAATTGCAAATAGGTAGGAGGAGATGACC
Downstream sequence
ATTATGAAGGAATGATTATGCAAGAGCTTATAATTGAATAGGATTTGAAAAAGGTGTCAGGATTTCCCCAGGAGAGTAGGGGAGCTTGTTTTCCTGGAAT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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