VISDB Viral Integration Site DataBase

VIS ID

TVIS44014327

Fusion event

HTLV-1-TMEM189 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr20

Cytoband

q13.13

Reference genome

Start

End

48759423/50142886 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-744-5p ; hsa-mir-181b-5p ; hsa-mir-627-3p ; hsa-mir-218-5p ; hsa-mir-636 ; hsa-mir-3607-5p ; hsa-mir-4257 ; hsa-mir-6847-5p ; hsa-mir-892c-5p ; hsa-mir-96-3p ; hsa-mir-6873-5p ; hsa-mir-6858-5p ; hsa-mir-4689 ; hsa-mir-1224-5p ; hsa-mir-3915 ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-765 ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-6760-5p ; hsa-mir-4779 ; hsa-mir-15b-5p ; hsa-mir-6838-5p ; hsa-mir-15a-5p ; hsa-mir-424-5p ; hsa-mir-16-5p ; hsa-mir-195-5p ; hsa-mir-497-5p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-2110 ; hsa-mir-4472 ; hsa-mir-4447 ; hsa-mir-92a-2-5p ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-7976 ; hsa-mir-3153 ; hsa-mir-1253 ; hsa-mir-6795-3p ; hsa-mir-6890-5p ; hsa-mir-3675-5p ; hsa-mir-548m ; hsa-mir-6515-5p ; hsa-mir-7847-3p ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-4330 ; hsa-mir-216a-5p ; hsa-mir-6795-5p ; hsa-mir-6810-5p ; hsa-mir-6079 ; hsa-mir-5087 ; hsa-mir-4652-5p ; hsa-mir-3191-3p ; hsa-mir-3144-5p ; hsa-mir-3202 ; hsa-mir-4533 ; hsa-mir-7112-3p ; hsa-mir-8069 ; hsa-mir-3179 ; hsa-mir-6743-5p ; hsa-mir-6716-5p ; hsa-mir-4688 ; hsa-mir-1322 ; hsa-mir-1272 ; hsa-mir-3121-3p ; hsa-mir-6818-5p ; hsa-mir-147a ; hsa-mir-4291 ; hsa-mir-511-5p ; hsa-mir-4711-3p ; hsa-mir-6830-3p ; hsa-mir-4445-5p ; hsa-mir-508-3p ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-922 ; hsa-mir-4761-5p ; hsa-mir-3617-3p ; hsa-mir-34a-3p ; hsa-mir-6766-3p ; hsa-mir-4782-3p ; hsa-mir-219a-5p ; hsa-mir-6878-5p ; hsa-mir-548e-5p ; hsa-mir-3065-3p ; hsa-mir-584-5p ; hsa-mir-3165 ; hsa-mir-6880-5p ; hsa-mir-8071 ; hsa-mir-5192 ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-4765 ; hsa-mir-1236-5p ; hsa-mir-496 ; hsa-mir-4456 ; hsa-mir-4693-3p ; hsa-mir-758-5p ; hsa-mir-218-2-3p ; hsa-mir-5586-3p ; hsa-mir-3174 ; hsa-mir-138-5p ; hsa-mir-188-3p ; hsa-mir-4433a-5p ; hsa-mir-604 ; hsa-mir-140-3p ; hsa-mir-3129-5p ; hsa-mir-199b-3p ; hsa-mir-199a-3p ; hsa-mir-1228-3p ; hsa-mir-2114-5p ; hsa-mir-5588-3p ; hsa-mir-4519 ; hsa-mir-4274 ; hsa-mir-4438 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac

Nearest miRNA

hsa-mir-103a-2/Upstream/278933; hsa-mir-1-1/Downstream/442900;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/29625, chr20-CpG: 90/Downstream/10522

Upstream sequence

tctgctgagaggaggtgacctctcagcagacacctggagtgagccatgtaggtgagagttctaggcacagagaatggcacatgcaaaagccctgaagtag

Downstream sequence

gaatgtatctgagagcaggtgacagacgcacagtcagggggccagcgtggcaggtgcagggtgacctagcatgagggtggctagaggaagctggggcagg