Basic Information
VIS ID
TVIS44014354
Fusion event
HTLV-1-LOC105376360 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
3680950/3638758 (Hg38)
End
3680950/3638758 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LOC105376360
Nearest miRNA
hsa-mir-5699/Upstream/1562669; hsa-mir-107/Downstream/352402;
Nearest TSS
ENST00000439456/Upstream/101727; ENST00000421629/Downstream/112309;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/82020, chr10-CpG: 19/Downstream/142839
Upstream sequence
CCTTCCTCCAACAAGACTACGAGAGTAGAGGGAGTTTGCCGAGTAGCTGGCTGCTGCCTGGGTGGAGGAAACCAGGGGTGGAGAGTCGCCCTTTTCTATC
Downstream sequence
TTTTCCATCCCTGGGGTTCACAGACCCTGTTCTTCTGTGGGTGTCCACAGGTCCAGAGGTGCAACCCTGCAGTGGGATGTCATAGGATGTGACCTTGGGC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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