Basic Information
VIS ID
TVIS44014379
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q42.13
Reference genome
GRCh37/hg19
Start
229318762/229183015 (Hg38)
End
229318762/229183015 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1H
Target gene
LOC105373158 ; LOC112267873
Nearest miRNA
hsa-mir-101-1/Upstream/720863; hsa-mir-1182/Downstream/1836813;
Nearest TSS
ENST00000473358/Upstream/88110; ENST00000323223/Downstream/44547;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/427811, chr1-CpG: 70/Downstream/87884
Nearby gene
MIR4454(No orient, 8214)
Upstream sequence
TCTCCCTCACCTCCACACTTTGCCTCTTTTCCCTTTTCTCCCAAAATAAGAGACTTTAAACAGCAAGCACTTAAAATAGCTTTTAGCCTTGCTTTAGTAT
Downstream sequence
AAGGTCCAGGGTACCATATGGTTTGGCCATTGGAAGAAAGCTGAAACACAGGCCTTTGTGGGTGTTAAAATTCAAGTAGCCGTTTCTAGCACTTTTCTCA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate