Basic Information
VIS ID
TVIS44014402
Fusion event
HTLV-1-LOC102724858 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
77211243/76299008 (Hg38)
End
77211243/76299008 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC102724858
Nearest miRNA
hsa-mir-124-1/Upstream/1593261; hsa-mir-10400/Downstream/667760;
Nearest TSS
ENST00000518652/Upstream/759139; ENST00000603284/Downstream/104990;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/890819, chr8-CpG: 59/Downstream/383012
Nearby gene
LINC01111(No orient, 107646)
Upstream sequence
taatcttatttctgactttaccaggaaaacttcttgtgcttccacattaagtatgatgctgtcttttgttctatgatacatatttgattatgttaagtaa
Downstream sequence
gtttctatgcaatcctgttgtactgagagaagggtattaattttctgcatctatagaaatgatcaaaaaacattcttacttattctgtaaatgtgatgaa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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