VISDB Viral Integration Site DataBase

VIS ID

TVIS44014423

Fusion event

HTLV-1-HSPE1-MOB4 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

q33.1

Reference genome

Start

End

198417250/197552526 (Hg38)

Orient

-

Location type

UTR3

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-let-7f-2-3p ; hsa-mir-101-3p ; hsa-mir-383-5p ; hsa-mir-569 ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-mir-2053 ; hsa-mir-4772-5p ; hsa-mir-5011-5p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-219a-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-508-3p ; hsa-mir-580-5p ; hsa-mir-590-3p ; hsa-mir-640 ; hsa-mir-374b-3p ; hsa-mir-4445-5p ; hsa-mir-4524a-5p ; hsa-mir-4782-3p ; hsa-mir-4524b-5p ; hsa-mir-6766-3p ; hsa-mir-6838-5p ; hsa-mir-3662 ; hsa-mir-2681-5p ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-550b-2-5p ; hsa-mir-5089-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-550a-5p ; hsa-mir-550a-3-5p ; hsa-mir-1271-3p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-210-5p ; hsa-mir-1233-3p ; hsa-mir-6889-3p ; hsa-mir-1225-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-1914-5p ; hsa-mir-6504-3p ; hsa-mir-512-3p ; hsa-mir-6769a-3p ; hsa-mir-4438 ; hsa-mir-4711-3p ; hsa-mir-944 ; hsa-mir-33a-3p ; hsa-mir-409-3p ; hsa-mir-144-3p ; hsa-mir-632 ; hsa-mir-4288 ; hsa-mir-6888-3p ; hsa-mir-5001-3p ; hsa-mir-378a-5p ; hsa-mir-346 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3120-5p ; hsa-mir-3653-5p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-498 ; hsa-mir-4279 ; hsa-mir-1976 ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-4532 ; hsa-mir-1247-3p ; hsa-mir-6843-3p ; hsa-mir-6848-3p ; hsa-mir-5587-5p ; hsa-mir-6801-5p ; hsa-mir-6131 ; hsa-mir-3663-5p ; hsa-mir-484 ; hsa-mir-3155b ; hsa-mir-3155a

Nearest miRNA

hsa-mir-10b/Upstream/8419415; hsa-mir-1244-1/Downstream/9230708;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/35949, chr2-CpG: 91/Downstream/152661

Upstream sequence

TATTTTCTTAGTGAATATTTATACTAAGGTAGTGACTGAGATTTGGTGATCTGGCTGAGTATTTTGAAACACATTTTGAATAATATGGCTTAGTGTTAAC

Downstream sequence

GGGGACTTAAATATGATTTTTTTTTCTTACTCATTTCACCTTCCCTGTACTGTATGTTTGGAATTGATCATAAAACATCTCCAAAAGAAAATAATCAGTT