Basic Information
VIS ID
TVIS44014425
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p23
Reference genome
GRCh37/hg19
Start
14803191/14802960 (Hg38)
End
14803191/14802960 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA6A
Nearest miRNA
hsa-mir-3691/Upstream/4363166; hsa-mir-10398/Downstream/1338596;
Nearest TSS
ENST00000381078/Upstream/203270; ENST00000474854/Downstream/219004;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/591447, chr6-CpG: 113/Downstream/441686
Nearby gene
JARID2(+443015) ;
Upstream sequence
CCCCAGTAGATTTCCATATGTTGTGCTAAAATCGCACTGGAGGCTGACTGAGCATTTGTGGCTTTTCAGAGATGCCAGTTTTGGTGAGGGGGTTGGGGGT
Downstream sequence
TGCTGGGGGCAGTCACCTGCATCGTGCAAGGATAGAAATAAATGATATCATCCCTAGGGCACAGAAAGCAGAGCTGTGGGGGCCTCTGGGTCGTGTCCCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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