Basic Information
VIS ID
TVIS44014426
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
54330805/54263112 (Hg38)
End
54330805/54263112 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA7A
Nearest miRNA
hsa-mir-1183/Upstream/9381312; hsa-mir-10399/Downstream/2692673;
Nearest TSS
ENST00000635602/Upstream/61888; ENST00000426205/Downstream/67585;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/1043613, chr7-CpG: 48/Downstream/278929
Nearby gene
HPVC1(-60691) ;
Upstream sequence
accagattttgtgtgaacagagtgagaactcacttctcactaagtggaaagcccaagccactcatgagggatccacccgcgtcatccaaaacctcccaac
Downstream sequence
aggcccacttccaacactgaggattacatttcaacatgagatttggacagggacaaatagccaaactctatcaCACCtatttcatgttttaaactgtgtt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate