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Viral Integration Site DataBase
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TVIS44014434
Basic Information
VIS ID
TVIS44014434
Fusion event
HTLV-1-NCOR2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.31
Reference genome
GRCh37/hg19
Start
124920592/124436046 (Hg38)
End
124920592/124436046 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
NCOR2
miRNAs that regulate target gene
hsa-mir-10a-5p
;
hsa-mir-10b-5p
;
hsa-mir-16-5p
;
hsa-mir-9-5p
;
hsa-mir-2110
;
hsa-mir-130b-5p
;
hsa-mir-20a-5p
;
hsa-mir-125b-5p
;
hsa-mir-100-5p
;
hsa-mir-30c-5p
;
hsa-mir-4459
;
hsa-mir-6757-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-3178
;
hsa-mir-6799-5p
;
hsa-mir-6785-5p
;
hsa-mir-6883-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-25-5p
;
hsa-mir-6797-5p
;
hsa-mir-1249-5p
;
hsa-mir-658
;
hsa-mir-2277-5p
;
hsa-mir-6133
;
hsa-mir-6130
;
hsa-mir-6129
;
hsa-mir-6127
;
hsa-mir-4510
;
hsa-mir-4419a
;
hsa-mir-6087
;
hsa-mir-6871-5p
;
hsa-mir-4756-5p
;
hsa-mir-1321
;
hsa-mir-4739
;
hsa-mir-195-5p
;
hsa-mir-15b-5p
;
hsa-mir-15a-5p
;
hsa-mir-34a-3p
;
hsa-mir-1266-5p
;
hsa-mir-3197
;
hsa-mir-3612
;
hsa-mir-3937
;
hsa-mir-4274
;
hsa-mir-4313
;
hsa-mir-4443
;
hsa-mir-4518
;
hsa-mir-4530
;
hsa-mir-4802-5p
;
hsa-mir-510-5p
;
hsa-mir-6085
;
hsa-mir-650
;
hsa-mir-6798-5p
;
hsa-mir-6807-5p
;
hsa-mir-6813-5p
;
hsa-mir-6858-3p
;
hsa-mir-7108-3p
Nearest miRNA
hsa-let-7i/Upstream/98804; hsa-mir-3612/Downstream/479501;
Nearest TSS
ENST00000382841/Upstream/5405;
ENST00000543970/Downstream/47723;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/9128
,
chr12-CpG: 28/Downstream/9280
Upstream sequence
gactaaatgccctaatgtatggagagcactcagaagagcgcctgcaacacaacaggcacCGGAAGGGCAGGGTGTGCGGGCATCCTCCTCGTCCTTACGC
Downstream sequence
ACGACCTGTCCCTGCAGCCTGCAGGTCTGAGGACAGGGCCCGTGTCACAGCAACTGCGAGCCTCACACACAGTAGGTGCTCCGTGACTACTGGCATCCAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL54
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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