Basic Information
VIS ID
TVIS44014440
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
67067720/69400484 (Hg38)
End
67067720/69400484 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/2318798; hsa-mir-548av/Downstream/3452837;
Nearest TSS
ENST00000575820/Upstream/1235; ENST00000582172/Downstream/571;
Nearest CpG islands
chr18-CpG: 174/Target, None/Upstream, None/Downstream
Nearby gene
DOK6(+564) ;
Upstream sequence
GAGGATTAGACACATGCGCACGATTGGTCTCTTTGTGTGCACCAGGAAGGGTCTGGCGTCGATTTACACTTCCTAACGGGGCAGAGACCTGGAACGGCCG
Downstream sequence
CGAGTGCTTGGGAATAAAAATGTACTGTAAACAAGGCCAATGAAATAAGTGTCTCGCTCCCGCTGGCCTTCCGCGTTGGAAGTGTCCCCACTGCCCTTTC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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