Basic Information
VIS ID
TVIS44014456
Fusion event
HTLV-1-NLGN4Y integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrY
Cytoband
q11.221
Reference genome
End
16635929/14524049 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12120/Upstream/1044783;
Nearest CpG islands
chrY-CpG: 22/Target, None/Upstream, None/Downstream
Upstream sequence
TCCCGTGTGTGTGGGTTACGACGTGGGTGGGAGTGGTGAGGCAAGCCGCAAAAGTGGGGTAGAGCTGGTGGTTTTGCTTCTTCGGAAGCCTTTGAGTGTG
Downstream sequence
GCCTGGACCTTAGATGGGGGTGCAGGGCGGTTTGCCGCTGCCACCCTCGGCACCATCTCTGAACTGCCCGCTTTTCCGGAGGAGCGGAAAAGTTGGAAGC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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