Basic Information
VIS ID
TVIS44014464
Fusion event
HTLV-1-LOC105370531 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
63643792/63177074 (Hg38)
End
63643792/63177074 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA14B
Target gene
LOC105370531
Nearest miRNA
hsa-mir-208a/Upstream/2528363; hsa-mir-1185-1/Downstream/917950;
Nearest TSS
ENST00000550708/Upstream/48860; ENST00000557133/Downstream/27040;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/130796, chr14-CpG: 103/Downstream/365753
Nearby gene
RHOJ(+27310) ;
Upstream sequence
ttggtatttcactttttcatataccagaagacttagaaatgaaagggatctgACTTTTTTGGAGAAGCTCTGCTAAGAGAAGTACGACCAGGTCATTTGT
Downstream sequence
GGGAAAATAGGCAATTCATCTAATAAAAACAGAGGCACCACTCACAAATACTTTTGCTCTGCTAGACATTCTATTTGGAGCTTTGTAATACCATACCATG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate