Basic Information
VIS ID
TVIS44014481
Fusion event
HTLV-1-CAPZA2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q31.2
Reference genome
End
116551814/116911760 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-6504-3p ; hsa-mir-15a-5p ; hsa-mir-107 ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-374b-3p ; hsa-mir-4524a-5p ; hsa-mir-4524b-5p ; hsa-mir-6838-5p ; hsa-mir-498 ; hsa-mir-7151-5p ; hsa-mir-1185-1-3p ; hsa-mir-136-5p ; hsa-mir-1185-2-3p ; hsa-mir-6884-3p ; hsa-mir-135b-5p ; hsa-mir-135a-5p ; hsa-mir-889-5p ; hsa-mir-8076 ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-605-5p ; hsa-mir-4284 ; hsa-mir-4772-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-6890-3p ; hsa-mir-4793-5p ; hsa-mir-937-5p ; hsa-mir-6848-3p ; hsa-mir-3152-3p ; hsa-mir-6843-3p ; hsa-mir-4483 ; hsa-mir-323a-5p ; hsa-mir-6823-5p ; hsa-mir-1293 ; hsa-mir-4279 ; hsa-mir-6778-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-325 ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-5582-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-4438 ; hsa-mir-6720-3p ; hsa-mir-4740-3p ; hsa-mir-6807-5p ; hsa-mir-150-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-512-3p ; hsa-mir-576-3p ; hsa-mir-5683 ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-576-5p ; hsa-mir-4263 ; hsa-mir-7977 ; hsa-mir-627-3p ; hsa-mir-4735-5p ; hsa-mir-380-3p ; hsa-mir-411-3p ; hsa-mir-379-3p ; hsa-mir-4495 ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-32-3p ; hsa-mir-1292-3p ; hsa-mir-186-3p ; hsa-mir-4731-5p ; hsa-mir-5089-5p ; hsa-mir-5589-5p ; hsa-mir-619-5p ; hsa-mir-6506-5p
Nearest miRNA
hsa-mir-10525/Upstream/2258305; hsa-mir-10399/Downstream/108451;
Upstream sequence
acagcactcattcagtgtttgttgagtaaatTCATGTCTGAGTTTGGGGAATTAAATGGTTGGTGGAAATACACAAAAgaagaacaggattgggaaggaa
Downstream sequence
tattgtgagctcagatttggacatcttggttttagataccagtagaATGAATGACTGTGAGGCAAAAATGTCCAGCAGTCAGGTCAATAGAAGGCTTGCC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate