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VISDB
Viral Integration Site DataBase
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TVIS44014493
Basic Information
VIS ID
TVIS44014493
Fusion event
HTLV-1-MED18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p35.3
Reference genome
GRCh37/hg19
Start
28658176/28331665 (Hg38)
End
28658176/28331665 (Hg38)
Orient
+
Location type
Intronic
Target gene
MED18
miRNAs that regulate target gene
hsa-mir-532-3p
;
hsa-mir-5089-5p
;
hsa-mir-6807-5p
;
hsa-mir-6866-5p
;
hsa-mir-877-5p
;
hsa-mir-4731-5p
;
hsa-mir-5589-5p
;
hsa-mir-4252
;
hsa-mir-6506-5p
;
hsa-mir-619-5p
;
hsa-mir-328-3p
;
hsa-mir-191-3p
;
hsa-mir-186-3p
;
hsa-mir-1273g-3p
;
hsa-mir-520h
;
hsa-mir-520g-3p
;
hsa-mir-512-3p
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-93-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
;
hsa-mir-106a-3p
;
hsa-mir-3191-5p
;
hsa-mir-1229-3p
;
hsa-mir-4430
;
hsa-mir-3652
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-3135b
;
hsa-mir-3663-5p
;
hsa-mir-7152-3p
;
hsa-mir-6824-3p
;
hsa-mir-6764-3p
;
hsa-mir-330-5p
;
hsa-mir-326
;
hsa-mir-518c-5p
;
hsa-mir-6862-3p
;
hsa-mir-6784-3p
;
hsa-mir-6511b-3p
;
hsa-mir-6511a-3p
;
hsa-mir-500b-3p
;
hsa-mir-454-3p
;
hsa-mir-4295
;
hsa-mir-3666
;
hsa-mir-301b-3p
;
hsa-mir-301a-3p
;
hsa-mir-130b-3p
;
hsa-mir-130a-3p
Nearest miRNA
hsa-mir-12136/Upstream/1777072; hsa-mir-101-1/Downstream/2407491;
Nearest TSS
ENST00000473358/Upstream/1382;
ENST00000633371/Downstream/37917;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/2509
,
chr1-CpG: 61/Downstream/37865
Upstream sequence
aagtgatatacttgccttggcctcccaaagtgctaggattacaggtatgagctgccgcgcctggcctaaaatacttaagtttttcatcctataaaactgc
Downstream sequence
aactctatacccattaaacactaattaccactcccctctatgccaaacccttagcaactatctttctaggtcctgtttctctgattttttttttttaaga
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL182
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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