Basic Information
VIS ID
TVIS44014494
Fusion event
HTLV-1-IL12RB2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
End
67793958/67328275 (Hg38)
Orient
-
Location type
Exonic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-101-1/Upstream/699758; hsa-mir-11399/Downstream/855243;
Upstream sequence
CACGTGGTTGTGTTTTGTTTACAGGCTAAGTGGACCAAAAAATTTAACCTGGCAGAAGCAATGTAAAGACATTTATTGTGACTATTTGGACTTTGGAATC
Downstream sequence
AACCTCACCCCTGAATCACCTGAATCCAATTTCACAGCCAAGGTTACTGCTGTCAATAGTCTTGGAAGCTCCTCTTCACTTCCATCCACATTCACATTCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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