Basic Information
VIS ID
TVIS44014495
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
117342691/116800069 (Hg38)
End
117342691/116800069 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/128252; hsa-mir-1182/Downstream/294574;
Nearest TSS
ENST00000473358/Upstream/45602; ENST00000496699/Downstream/109462;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/132070, chr1-CpG: 126/Downstream/109512
Nearby gene
CD2(+30840) ;
Upstream sequence
ACATGTTGATCTACTGTGGCAAAGAACTAAGAAATGTGTACAAAACAGCTCATTCTCTCAAAATGCTTAATTTCTAGCCAGAGAGGTGATATATGGAAGG
Downstream sequence
ATGAGTTTTTTTCCTTCTTGCTCACCATCCTTTCCTCTTTCCAAAGAGTAAATCTCACAAGGCTACAATAATAGAGGAAGGGTTTTTTGGTTGTGACACC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate