Basic Information
VIS ID
TVIS44014506
Fusion event
HTLV-1-ABI1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
27147774/26858845 (Hg38)
End
27147774/26858845 (Hg38)
Orient
-
Location type
Intronic
Target gene
ABI1
Nearest miRNA
hsa-mir-1265/Upstream/2583064; hsa-mir-107/Downstream/1430413;
Nearest TSS
ENST00000439456/Upstream/35555; ENST00000477034/Downstream/2018;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/160686, chr10-CpG: 85/Downstream/1392
Upstream sequence
CATTACAACATACAACTACCTGAAAAAGTAATAGTACACAGACAGGTTAAAACACGTTTACAGTTACTAACAGTTGCCAACACATAGTTACCACACTATA
Downstream sequence
TACTTGTCAGATTTCCCAACATGCAAAACAAAAAGGAGCCACCCCTGTATGAAGCACTTATCTACTGACTTCTACAGAGAACACATAACTTTTCTGGAAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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