Basic Information
VIS ID
TVIS44014530
Fusion event
HTLV-1-CLEC4A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.31
Reference genome
GRCh37/hg19
Start
8259310/8106714 (Hg38)
End
8259310/8106714 (Hg38)
Orient
-
Location type
Intronic
Target gene
CLEC4A
Nearest miRNA
hsa-mir-141/Upstream/1142523; hsa-let-7i/Downstream/1132753;
Nearest TSS
ENST00000382841/Upstream/11436; ENST00000641376/Downstream/16918;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/24290, chr12-CpG: 42/Downstream/73478
Nearby gene
NECAP1(+8937) ;
Upstream sequence
agctgtattccgaggtattttattttatgattattttttgtggcattttgaatggaattacatttttgatttgcctctcagcttggacgttggatttttg
Downstream sequence
tacactgattttctatcttgaaactttactgaagttgtttatcagatctagaagcttttgggcagagactgtgggttttctaggtatagaatcatctcat
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate