Basic Information
VIS ID
TVIS44014569
Fusion event
HTLV-1-UNC13C integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
54156256/53864059 (Hg38)
End
54156256/53864059 (Hg38)
Orient
+
Location type
Intronic
Target gene
UNC13C
miRNAs that regulate target gene
hsa-mir-128-3p
Nearest miRNA
hsa-mir-10393/Upstream/1586859; hsa-mir-11181/Downstream/1508881;
Nearest TSS
ENST00000557528/Upstream/101181; ENST00000561210/Downstream/110891;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/104252, chr15-CpG: 52/Downstream/1332485
Nearby gene
WDR72(-104397) ;
Upstream sequence
actttgaggtccatgttccatgctggctgccagagttcctcatttggaacatttcagctaccacagtggtaatgtccttgtacatacacttttttggctg
Downstream sequence
ctttctatgccttgttttacttttccactgtcctttctgtgtctcctgacatcttcacccacataaatgaccagcacttgaatccctgtctctaggtctt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate