Basic Information
VIS ID
TVIS44014585
Fusion event
HTLV-1-LOC105371742 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q12
Reference genome
GRCh37/hg19
Start
33102309/34775290 (Hg38)
End
33102309/34775290 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105371742
Nearest miRNA
hsa-mir-1180/Upstream/2425088; hsa-mir-10226/Downstream/2258455;
Nearest TSS
ENST00000595228/Upstream/49120; ENST00000578339/Downstream/83756;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/136876, chr17-CpG: 64/Downstream/185865
Nearby gene
TMEM132E(+135972) ;
Upstream sequence
GGTATGAGAGGCTCCCCTCCGAGAAGCAGACACAGTCCCTGGGAGAGTGCAGTCTGATGGGGGAGACACAGACCCTATCCCGGCAGATCTGCCAGTATGA
Downstream sequence
TTTCTGAGTTCAAGAACTCCAGTCTGAGAGAGGAAGACAACACACAAAGATGGACTTGCAAATGCCCACCAGTGAGAAGGTCCCCTGACCTTCTGTCACA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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