Basic Information
VIS ID
TVIS44014591
Fusion event
HTLV-1-AMZ2P1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
62964835/64968717 (Hg38)
End
62964835/64968717 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
AMZ2P1
Nearest miRNA
hsa-mir-10226/Upstream/146615; hsa-mir-1250/Downstream/1818355;
Nearest TSS
ENST00000595228/Upstream/25455; ENST00000581796/Downstream/83192;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/2530, chr17-CpG: 81/Downstream/6680
Upstream sequence
AGAAATACACTCATTCTTATACTTTGTTTCTAGCATGATAGGATATTTTTTCTCAACTTGCTGAATATTCTACAAGGCATTATATTAATTTGACATGTAT
Downstream sequence
GTATATACATATATAAGTGTCCACACAGGCATGGGTAGACATATGTATGTGAAAACACATGTGTAGACATTTCTGTGCAGTCACCTGAATGCAGTCATAC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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